What is PDGF+?

PDGF+ is a bioengineered growth factor therapy designed to signal the skin to regenerate and repair. Growth factors are naturally occurring proteins in the body that play a critical role in cellular renewal, collagen production, and tissue healing.

Unlike treatments that simply add volume or temporarily improve appearance, PDGF+ works at the cellular level—supporting healthier, stronger skin over time.

PDGF+ vs. PRP: What’s the Difference?

Both PDGF+ and PRP (Platelet-Rich Plasma) are regenerative treatments designed to support the body’s natural healing and collagen production. While they share a similar goal, the way they are created, delivered, and controlled is very different.

PRP (Platelet-Rich Plasma)

PRP is derived from the patient’s own blood, which is drawn, spun in a centrifuge, and re-injected or applied topically.

Key considerations with PRP:

Requires a blood draw
Results vary significantly from patient to patient
Concentration and quality depend on individual biology
Less predictable dosing and consistency

PRP can be effective, but outcomes are inherently variable.

PDGF+ (Platelet-Derived Growth Factor Therapy)

PDGF+ is a bioengineered growth factor therapy designed to deliver consistent, targeted regenerative signaling without relying on a blood draw.

Key advantages of PDGF+:

No blood draw required
Precisely formulated and standardized
Consistent concentration and dosing
Predictable, repeatable results
Ideal for delicate areas like the under-eyes

Because PDGF+ is engineered for consistency, it allows providers to treat with greater precision—particularly in areas where control and subtlety matter most.

Why We Prefer PDGF+ at Capizzi MD

At Capizzi MD, we prioritize treatments that are reliable, controlled, and aligned with long-term outcomes. While PRP may still have a role in regenerative medicine, PDGF+ allows us to offer a more refined approach—especially for facial skin rejuvenation and under-eye treatments where variability is not ideal.

How We Use PDGF+ at Capizzi MD

PDGF+ Injectable (Under-Eye Rejuvenation)

The under-eye area is one of the most delicate and challenging regions to treat. PDGF+ injectable therapy is used to support tissue quality and skin integrity rather than adding bulk or altering facial structure.

Common goals include:

Improving crepey or thinning skin
Supporting collagen production
Enhancing skin texture and quality
Reducing the appearance of fatigue over time

This treatment is ideal for patients seeking a subtle, regenerative approach rather than traditional filler.

PDGF+ Topical (Microneedling, Hydrafacial, or Laser)

When applied topically during aesthetic treatments, PDGF+ is infused into the dermis – helping to enhance healing and optimize results.

Benefits of adding PDGF+ include:

Accelerated recovery time
Improved skin texture and tone
Enhanced collagen stimulation
More noticeable, longer-lasting results

PDGF+ can be paired with microneedling, Hydrafacials, or laser treatments.

Why Capizzi MD

We are intentionally selective about the regenerative therapies we offer. PDGF+ is used thoughtfully, conservatively, and only when it aligns with the patient’s long-term skin health goals.

At Capizzi MD, regenerative treatments are:

Integrated into a comprehensive treatment plan
Selected for safety, quality, and consistency
Performed by experienced medical providers

What Results Can I Expect?

PDGF+ is not an instant-gratification treatment. Results develop gradually as the skin responds and regenerates.

Patients often notice:

Improved skin quality and texture
Healthier, more resilient skin
Continued improvement over weeks to months

Because PDGF+ supports natural processes, results are subtle, refined, and progressive.

have a question?

FAQ: PDGF+ at Capizzi MD

Is PDGF+ a filler?

No. PDGF+ does not add volume or contour the face. It works by supporting cellular regeneration and improving skin quality.

How is PDGF+ different from PRP?

PDGF+ is a bioengineered growth factor therapy that has been used for over 15 years in wound care to provide cellular regeneration benefits to patients. Unlike PRP, it does not rely on blood draw or individual variability, allowing for consistency and precision in treatment.

Is PDGF+ FDA approved?

The growth factor utilized in PDGF+ is FDA-approved for specific medical and regenerative applications such as wound healing, bone regeneration, and soft tissue repair. It’s been used in millions of patients with a strong track record of safety and efficacy.

Is there downtime?

Downtime depends on how PDGF+ is used.

Injectable treatments: Minimal downtime; mild swelling or bruising may occur.
Topical use with microneedling or laser: Downtime mirrors that of the primary treatment, but is typically accelerated.

How many treatments are recommended?

Treatment plans are individualized. Some patients benefit from a series, while others incorporate PDGF+ periodically as part of ongoing skin maintenance.

Who is a good candidate?

Patients looking to improve skin quality, thin or crepey under-eyes, or enhance the results of microneedling or laser treatments may be excellent candidates. A consultation is required to determine appropriateness.

Schedule a Consultation

PDGF+ is best used as part of a customized treatment plan. Our team will help determine whether PDGF+ injectable therapy or a regenerative add-on aligns with your goals.

Schedule your consultation with Capizzi MD to explore regenerative skin treatments designed for longevity, balance, and refined results.

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